Main Sequence is CSIRO's venture capital fund, created to commercialise Australia's deep tech and scientific research. The firm invests in companies building transformative technologies at the intersection of science and entrepreneurship, with a unique pipeline of opportunities from Australia's national science agency.
Main Sequence backs founders who are turning breakthrough scientific research into scalable businesses across sectors including quantum computing, space technology, synthetic biology, advanced materials, and AI. The firm's CSIRO connection provides portfolio companies with unparalleled access to world-class scientific infrastructure and talent.
As Australia's science-to-startup bridge, Main Sequence occupies a unique position in the venture ecosystem — identifying commercial potential in research outputs before anyone else and providing the capital, mentorship, and industry connections to bring deep technology to market.
Melbourne & Sydney, Australia
"We invest at the intersection of science and entrepreneurship — turning breakthrough research into the companies that will shape Australia's future."
Apply to the Apex Startup Discovery Program
Aligned with Main Sequence Ventures's investment focus. Precondition: You must be an Apex Participant to submit. Registration is complimentary and includes 2 Golden Ads. This project is part of Apex Master Expos.
Apex Ecosystem with Golden Ads
"Who I Am · What I Want"
Complimentary for Apex Participants. Become an Apex Participant at myapex.me — registration is complimentary and includes 2 Golden Ads. Part of Apex Master Expos.
Apex is a living ecosystem — one of its kind. A decentralized, member-owned global business platform across 80+ countries where preferred venture partners such as Main Sequence Ventures can explore early-stage innovation quietly and selectively, while founders showcase on their MySite and gain clarity on what long-term investors truly seek. No middleman. By members, for members.